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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2213434Generated: October 27, 2026

1-(p-Chlorophenyl)cyclopropanecarboxylic acid → 1-(4-Chlorophenyl)-N-(3-{4-[3-(propionylamino)phenyl]-1-piperidinyl}propyl)cyclopropanecarboxamide

https://huagongshe.com/reaction/2213434

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(p-Chlorophenyl)cyclopropanecarboxylic acidHCID 98606—
ReactantN-{3-[1-(3-aminopropyl)4-piperidinyl]phenyl}propanamideHCID 21957142—
Product1-(4-Chlorophenyl)-N-(3-{4-[3-(propionylamino)phenyl]-1-piperidinyl}propyl)cyclopropanecarboxamideHCID 21957218—

Reaction Steps

Example 63 was prepared from 1-(4-chlorophenyl)cyclopropanecarboxylic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}propanamide according to the procedures described in Scheme 10: ESMS m/e: 468.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07105544B2
Source datasetuspto-grants-2006_09
ORD IDord-0bd8f1b421d3452faae8327390027cf1
Source noteuspto-grants-2006_09