HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Bis(4-fluorophenyl)acetic acid → N-{3-[4-(3-{[(dimethylamino)carbonyl]amino}phenyl)-1-piperidinyl]propyl}-2,2-bis(4-fluorophenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Bis(4-fluorophenyl)acetic acid | HCID 13511684 | — |
| Reactant | N'-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}-N,N-dimethylurea | HCID 21957254 | — |
| Product | N-{3-[4-(3-{[(dimethylamino)carbonyl]amino}phenyl)-1-piperidinyl]propyl}-2,2-bis(4-fluorophenyl)acetamide | HCID 21957240 | — |
Reaction Steps
Example 139 was prepared from bis(4-fluorophenyl)acetic acid and N′-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}-N,N-dimethylurea according to the procedures described in Scheme 9: ESMS m/e: 535.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105544B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-2fb648812c3145fc82e14f1605d6f845 |
| Source note | uspto-grants-2006_09 |