4-Isopropylaniline → N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine

HRID 2213587Notes

Reaction equation

HRID 2213587 reaction equation
[CH3:1][N:2]([CH3:11])[C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[CH:12]([C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1)([CH3:14])[CH3:13]>>[CH3:1][N:2]([CH3:11])[C:3]1[CH:10]=[CH:9][C:6]([CH2:7][NH:19][C:18]2[CH:20]=[CH:21][C:15]([CH:12]([CH3:14])[CH3:13])=[CH:16][CH:17]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 74644-IsopropylanilineHCID 74794-(Dimethylamino)Benzaldehyde

Product 1

HCID 21957887N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamineYield 68.7%

Procedure

By the reaction and treatment in the same manner as in Preparation Example 1 using 4-dimethylaminobenzaldehyde (11 g) and 4-isopropylaniline (10 g) as starting materials, [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (13.6 g) was obtained. melting point: 71–73° C.

Workup

  1. customBy the reaction and treatment in the same manner

Sources & evidence

ORD record
ord-bdcfab723de8442fa42b2ef7d3694995
Source dataset
uspto-grants-2006_09
Patent number
US07105567B2

Reaction notes

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