Cuminaldehyde → 4-(1-Methylethyl)-N-[4-(1-methylethyl)phenyl]benzenemethanamine

HRID 2213589Notes

Reaction equation

[CH:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[CH:12]([C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1)([CH3:14])[CH3:13]>>[CH:12]([C:15]1[CH:21]=[CH:20][C:18]([NH:19][CH2:8][C:7]2[CH:10]=[CH:11][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=2)=[CH:17][CH:16]=1)([CH3:14])[CH3:13]

Participants

Reactant 2

HCID 326Cuminaldehyde

HCID 74644-Isopropylaniline

Product 1

HCID 219579374-(1-Methylethyl)-N-[4-(1-methylethyl)phenyl]benzenemethanamineYield 96.1%

Procedure

By the reaction and treatment in the same manner as in Preparation Example 1 using 4-isopropylbenzaldehyde (1.5 g) and 4-isopropylaniline (1.4 g) as starting materials, (4-isopropylphenyl)[(4-isopropylphenyl)methyl]amine (2.6 g) was obtained.

Workup

customBy the reaction and treatment in the same manner

Sources & evidence

ORD record: ord-8a9da7aae5be4b599812c6e0f78dd71d
Source dataset: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07105567B2

Reaction notes

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