HRID2213938

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@@]2(CC=C(C)C)C(=O)[C@]1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O

HCID441298

CHEBI:5834

C35H52O4

HCID21226445

未命名化合物

PRODUCTS

生成物

结构：CC(C)=CCCC1(C)C(CC=C(C)C)CC2(CC=C(C)C)C(=O)C1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O

HCID3662

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

2 g of hyperforin (M. W. =536,01) are dissolved in 20 ml of THF under magnetic stirring; the solution is added with LiAlH4 in strong excess (1 g, 0.026 mol, M. W.=38). The progress of the reaction is monitored by TLC (eluent petroleum ether/EtOAc 9:1). After ten minutes the reaction is completed.

WORKUP

后处理

waitAfter ten minutes the reaction is completed

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6805081d48f44c5ba8b157f9bf99e780
来源数据集: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07105705B2
来源说明: uspto-grants-2006_09

反应 SMILES

[CH3:1][CH:2]([C:4]([C@@:6]12[C@@:16]([CH2:18][CH2:19][CH:20]=[C:21]([CH3:23])[CH3:22])([CH3:17])[C@@H:15]([CH2:24][CH:25]=[C:26]([CH3:28])[CH3:27])[CH2:14][C@@:11]([CH2:29][CH:30]=[C:31]([CH3:33])[CH3:32])([C:12]1=[O:13])[C:10]([OH:34])=[C:9]([CH2:35][CH:36]=[C:37]([CH3:39])[CH3:38])[C:7]2=[O:8])=[O:5])[CH3:3].[H-].[H-].[H-].[H-].[Li+].[Al+3]>C1COCC1>[CH3:3][CH:2]([C:4]([C:6]12[C:16]([CH2:18][CH2:19][CH:20]=[C:21]([CH3:22])[CH3:23])([CH3:17])[CH:15]([CH2:24][CH:25]=[C:26]([CH3:27])[CH3:28])[CH2:14][C:11]([CH2:29][CH:30]=[C:31]([CH3:33])[CH3:32])([C:12]1=[O:13])[C:10]([OH:34])=[C:9]([CH2:35][CH:36]=[C:37]([CH3:39])[CH3:38])[C:7]2=[O:8])=[O:5])[CH3:1]