反应详情

A solution of 18.0 g (104 mmol) of 4-amino-2-chloro-3-nitropyridine in 120 ml dimethylsulphoxide and 30 ml of water was stirred for four hours at 130° C. The solution was then cooled and left to stand overnight while cooling with ice. The product that crystallised out was suction filtered, washed with a little water and dried at 50° C.

1. temperatureThe solution was then cooled
2. waitleft
3. temperaturewhile cooling with ice
4. customThe product that crystallised out
5. filtrationfiltered
6. washwashed with a little water
7. customdried at 50° C.