HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 21948348, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-(6-Chloronaphthalene-2-sulfonyl)-1-{[4-ethoxycarbonylamino-1-(2-methyl-4-pyridyl)-4-piperidinyl]methyl}-2-piperazinone | HCID 21948295 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 21948348 | HCID 21948348 | 157.9% |
Reaction Steps
4-(6-Chloronaphthalene-2-sulfonyl)-1-{[4-ethoxycarbonylamino-1-(2-methyl-4-pyridyl)-4-piperidinyl]methyl}-2-piperazinone (215 mg) was suspended in ethyl acetate (10 ml), a 4N hydrochloric acid solution in ethyl acetate (0.3 ml) was added, and the resulting crystals were filtered off to obtain the title compound (180 mg) as colorless powders.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07109200B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-7d3ea04a17704e1dbac33868bca9ad03 |
| Source note | uspto-grants-2006_09 |