HCID 11788638, compound → HCID 21055355, compound

HRID 2215260Notes

Reaction equation

HRID 2215260 reaction equation
[NH2:1][C@H:2]1[CH2:8][S:7][C:6]2[CH:9]=[CH:10][CH:11]=[CH:12][C:5]=2[O:4][CH2:3]1.O[C:14]1C=CC(C)=CC=1S>>[NH2:1][C@H:2]1[CH2:8][S:7][C:6]2[CH:9]=[C:10]([CH3:14])[CH:11]=[CH:12][C:5]=2[O:4][CH2:3]1

Participants

3

Reactant 2

HCID 11788638HCID 11788638, compoundHCID 123069612-hydroxy-5-methylthiophenol

Product 1

HCID 21055355HCID 21055355, compound

Procedure

The title compound (Ib) is prepared according to a reaction sequence identical to that employed for the synthesis of 3-(R)-amino-3,4-dihydro-2H-1,5-benzoxathiepine (Ia-1) but using, as starting material, 2-hydroxy-5-methylthiophenol (IVb) instead of 2-hydroxythiophenol. The title compound (Ib) is obtained in the form of a yellow oil.

Workup

  1. customThe title compound (Ib) is prepared

Sources & evidence

ORD record
ord-f3f0d9c83f3149908bba3a0878dc450c
Source dataset
uspto-grants-2006_09
Patent number
US07109234B2

Reaction notes

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