Sulfuryl chloride → HCID 86598000, compound

HRID 2215288Notes

Reaction equation

HRID 2215288 reaction equation
[C:1](=[O:18])(SCC)[O:2][O:3][CH:4]([O:8][C:9](=[O:14])[C:10]([CH3:13])([CH3:12])[CH3:11])[CH:5]([CH3:7])[CH3:6].S(Cl)([Cl:22])(=O)=O>C(Cl)Cl>[Cl:22][C:1]([O:2][O:3][CH:4]([O:8][C:9](=[O:14])[C:10]([CH3:13])([CH3:12])[CH3:11])[CH:5]([CH3:7])[CH3:6])=[O:18]

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 86597998HCID 86597998, compound

Product 1

HCID 86598000HCID 86598000, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of (45) (4.76 mmol) in CH2Cl2 at 0° C. was treated with sulfuryl chloride (1.1 mmol) under N2 for 10 min, then the reaction mixture was concentrated to dryness in vacuo to afford the crude chloroformate (46) in quantitative yield, which used in the next step without further purification. 1H NMR (CDCl3, 400 MHz): δ 1.00 (d, 6H), 1.20 (d, 9H), 2.143 (m, 1H), 6.54 (d, 1H).

Workup

  1. concentrationthe reaction mixture was concentrated to dryness in vacuo

Sources & evidence

ORD record
ord-2b1a36f8e30c41c3b712c2003a89d10c
Source dataset
uspto-grants-2006_09
Patent number
US07109239B2

Reaction notes

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