HCID 21941232, compound → HCID 21941239, compound

HRID 2216245Notes

Reaction equation

HRID 2216245 reaction equation
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([O:14][CH3:15])=[O:13])=[CH:7][C:6]=1[N+:16]([O-])=O)(=[O:3])[CH3:2]>CO.[Pd]>[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([O:14][CH3:15])=[O:13])=[CH:7][C:6]=1[NH2:16])(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 21941232HCID 21941232, compound

Product 1

HCID 21941239HCID 21941239, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Methyl 4-acetamido-3-nitrophenylacetate (40 g, 0.159 mol)) was dissolved in methanol (400 ml) and hydrogenated at 5 bar over a 5% palladium on carbon catalyst. The catalyst was removed by filtration and the filtrate evaporated in vacuo to give methyl 4-acetamido-3-aminophenylacetate.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-518b62b384f94e299a8bfbff546c9370
Source dataset
uspto-grants-2006_09
Patent number
US07112553B1

Reaction notes

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