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Epibromohydrin → Tert-butyldimethyl(4-(oxiran-2-ylmethoxy)phenoxy)silane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Epibromohydrin | HCID 18430 | — |
| 反応物 | 4-(tert-Butyldimethylsiloxy)phenol | HCID 597388 | — |
| 生成物 | Tert-butyldimethyl(4-(oxiran-2-ylmethoxy)phenoxy)silane | HCID 19385012 | 21% |
反応手順
Synthesis followed SP3a, using 4.1 mmol 4-(tert-Butyl-dimethyl-silanyloxy)-phenol and racemic epibromohydrine to give the title compound upon purification by Flash Master Personal (20 g silica gel cartridge, PE to PE/ethyl acetate 15:1) with 21% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08207174B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-95e5a9dc1d794b0b99703425051ff954 |
| 出典メモ | uspto-grants-2012_06 |