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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216351Generated: November 1, 2026

Trifluoroacetic acid → HCID 21942300, compound

https://huagongshe.com/reaction/2216351

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 21942295HCID 21942295—
ProductHCID 21942300HCID 2194230073.8%

Reaction Steps

A mixture of 505 mg of 2-benzyl-1-methoxymethyloxy-4-(2-pyrrolidinon-1-yl)benzene and 5 ml of trifluoroacetic acid was stirred at room temperature for 1 hour. The reaction mixture was evaporated, and the residue was purified by silica gel column chromatography with 30–60% ethyl acetate/hexane, to give 320 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112593B2
Source datasetuspto-grants-2006_09
ORD IDord-f3733ac3a6034053843521419ffa465f
Source noteuspto-grants-2006_09