Diethanolamine → 5-Amino-2-[bis(2-hydroxyethyl)amino]benzonitrile

HRID 2216390Notes

Reaction equation

HRID 2216390 reaction equation
Cl[C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-])=O)=[CH:6][C:3]=1[C:4]#[N:5].[NH:13]([CH2:17][CH2:18][OH:19])[CH2:14][CH2:15][OH:16]>>[NH2:10][C:7]1[CH:8]=[CH:9][C:2]([N:13]([CH2:17][CH2:18][OH:19])[CH2:14][CH2:15][OH:16])=[C:3]([CH:6]=1)[C:4]#[N:5]

Participants

3

Reactant 2

HCID 8113DiethanolamineHCID 855042-Chloro-5-nitrobenzonitrile

Product 1

HCID 219423665-Amino-2-[bis(2-hydroxyethyl)amino]benzonitrileYield 77.7%

Procedure

By the reaction and treatment in the same manner as in Starting Material Synthetic Example 4 using 2-chloro-5-nitrobenzonitrile (25.5 g) and diethanolamine (102 g), the title compound (24 g) was obtained. melting point: 38° C.

Workup

  1. customBy the reaction and treatment in the same manner as

Sources & evidence

ORD record
ord-ef298106cab44f2f84d07155a72e4654
Source dataset
uspto-grants-2006_09
Patent number
US07112594B2

Reaction notes

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