HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Piperazinecarboxylic acid, ethyl ester → 1-(Oxan-4-yl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Piperazinecarboxylic acid, ethyl ester | HCID 8431 | — |
| Reactant | Tetrahydro-4H-pyran-4-one | HCID 121599 | — |
| Product | 1-(Oxan-4-yl)piperazine | HCID 21942315 | 39% |
Reaction Steps
By the reaction and treatment in the same manner as in Starting Material Synthetic Example 10 using 1-ethoxycarbonylpiperazine (50 g) and 2,3,5,6-tetrahydropyran-4-one (34 g), the title compound (21 g) was obtained. boiling point: 95-100° C./5 mmHg
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07112594B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-fd2ef17b5cfd485a8d92e094603fa3c0 |
| Source note | uspto-grants-2006_09 |