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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216405Generated: October 31, 2026

5-fluoro-2-methyl-1H-indole-3-carboxylic acid → HCID 21942375, compound

https://huagongshe.com/reaction/2216405

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-fluoro-2-methyl-1H-indole-3-carboxylic acidHCID 13536275—
Reactant5-Amino-2-(4-hydroxypiperidin-1-yl)benzonitrileHCID 21942313—
ProductHCID 21942375HCID 2194237532.8%

Reaction Steps

By the reaction and treatment in the same manner as in Example 6 using 5-fluoro-2-methyl-1H-indole-3-carboxylic acid (0.9 g) and 5-amino-2-(4-hydroxypiperidin-1-yl)benzonitrile (1.1 g), the title compound (0.6 g) was obtained. melting point: 169-171° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112594B2
Source datasetuspto-grants-2006_09
ORD IDord-ec993d54c224478b800ec7bc55bb052f
Source noteuspto-grants-2006_09