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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216409Generated: October 30, 2026

Benzo(b)thiophene-2-carboxylic acid → HCID 21942334, compound

https://huagongshe.com/reaction/2216409

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
Reactant5-Amino-2-(4-hydroxypiperidin-1-yl)benzonitrileHCID 21942313—
ProductHCID 21942334HCID 2194233440.3%

Reaction Steps

By the reaction and treatment in the same manner as in Example 6 using benzo[b]thiophene-2-carboxylic acid (4 g) and 5-amino-2-(4-hydroxypiperidin-1-yl)benzonitrile (4 g), the title compound (2.8 g) was obtained. melting point: 224-225° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112594B2
Source datasetuspto-grants-2006_09
ORD IDord-5437f3b240ad4c38856c5b3d818639cd
Source noteuspto-grants-2006_09