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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216417Generated: November 1, 2026

3-Chloro-1-benzothiophene-2-carboxylic acid → HCID 21942357, compound

https://huagongshe.com/reaction/2216417

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-1-benzothiophene-2-carboxylic acidHCID 307964—
Reactant5-Amino-2-(4-morpholinopiperidin-1-yl)benzonitrileHCID 21942389—
ProductHCID 21942357HCID 2194235752.2%

Reaction Steps

By the reaction and treatment in the same manner as in Example 6 using 3-chlorobenzo[b]thiophene-2-carboxylic acid (1.1 g) and 5-amino-2-(4-morpholinopiperidin-1-yl)benzonitrile (1.5 g), the title compound (1.3 g) was obtained. melting point: 227-228° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112594B2
Source datasetuspto-grants-2006_09
ORD IDord-1d516ed0f7cf402585309ff3a51c6197
Source noteuspto-grants-2006_09