Methylamine → HCID 21943408, compound

HRID 2216537Notes

Reaction equation

HRID 2216537 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([CH:6]2[O:8][CH2:7]2)=[CH:4][CH:3]=1.[CH3:11][NH2:12]>>[CH3:11][NH:12][CH2:7][CH:6]([OH:8])[C:5]1[CH:9]=[CH:10][C:2]([CH3:1])=[CH:3][CH:4]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 1081112-(4-Methylphenyl)oxirane

Product 1

HCID 21943408HCID 21943408, compoundYield 71.2%

Procedure

4-Methyl styrene oxide(1.0 g, 8.0 mmol) and 3 ml of methylamine in methanolic solution(28%) were charged into a flask. The flask was sealed and put in a refrigerator for 5–7 days. The solution was concentrated and the residue crystallized from ether, the title compound was obtained as white needle crystals, mp. 90.5–93.2° C., yield 71.2%.

Workup

  1. customThe flask was sealed
  2. waitput in a refrigerator for 5–7 days
  3. concentrationThe solution was concentrated
  4. customthe residue crystallized from ether

Sources & evidence

ORD record
ord-1791eae5abda447abdd3481695cf0ced
Source dataset
uspto-grants-2006_09
Patent number
US07112605B2

Reaction notes

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