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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2217173Generated: November 2, 2026

HCID 21911719, compound → HCID 28807918, compound

https://huagongshe.com/reaction/2217173

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21911719HCID 21911719—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 28807918HCID 28807918—

Reaction Steps

To N-(2,6-dimethylphenyl)-3-(4-carbobenzyloxypiperazinyl)propanamide (1.3 g) in 10 mL of methanol was added 10% Pd/C, and the mixture was hydrogenated at 30 psi for 24 hours. The mixture was filtered, and the solvent was removed from the filtrate under reduced pressure, to afford N-(2,6-dimethylphenyl)-3-piperazinylpropanamide, a compound of formula (4),which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07407960B2
Source datasetuspto-grants-2008_08
ORD IDord-4117c3bd965e4fc4859b0284c295f070
Source noteuspto-grants-2008_08