Hydrochloric Acid → 123022-35-5

HRID 2217643Notes

Reaction equation

HRID 2217643 reaction equation
C([O:4][C:5]1[CH:10]=[CH:9][C:8](/[CH:11]=[CH:12]/[CH:13]=[CH:14]/[C:15]([O:17]C)=[O:16])=[CH:7][C:6]=1[O:19][CH3:20])(=O)C.[OH-].[Na+].O.Cl>CO>[OH:4][C:5]1[CH:10]=[CH:9][C:8](/[CH:11]=[CH:12]/[CH:13]=[CH:14]/[C:15]([OH:17])=[O:16])=[CH:7][C:6]=1[O:19][CH3:20]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 14798Sodium HydroxideHCID 58843894HCID 58843894, compound

Product 1

HCID 14053117123022-35-5

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

Methyl 5-(4-Acetoxy-3-methoxyphenyl)-penta-2E,4E-dienoate (400 mg, 1.45 mmol) [Example 1] was dissolved in 60 mL MeOH, 20 mL of 5% NaOH and 40 mL of water were added, and the mixture was stirred for 24 h at room temperature. The mixture was acidified to pH 2 with 5% HCl, methanol was evaporated and the compound was extracted with ethyl acetate. The organic layer was dried with Na2SO4 and evaporated.

Workup

  1. customwas evaporated
  2. extractionthe compound was extracted with ethyl acetate
  3. dry with materialThe organic layer was dried with Na2SO4
  4. customevaporated

Sources & evidence

ORD record
ord-012090bba0ec4a39b824f65abe05e4db
Source dataset
uspto-grants-2008_08
Patent number
US07407989B2

Reaction notes

Loading…