反应详情

Prepared according to the method of example 18, using 5-quinolinamine (230 mg) and 1-methyl-cyclohexaneacetic acid (250 mg). Purification (SiO2, methanol:dichloromethane 1:9 as eluant) followed by recrystallisation from methanol/ethyl acetate gave the title compound as a colourless solid (80 mg).

1. customPrepared
2. customPurification (SiO2, methanol:dichloromethane 1:9 as eluant)
3. customfollowed by recrystallisation from methanol/ethyl acetate