HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanepropanoic acid → N-5-Quinolinyl-cyclopentanepropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanepropanoic acid | HCID 8818 | — |
| Reactant | 5-Aminoquinoline | HCID 11911 | — |
| Product | N-5-Quinolinyl-cyclopentanepropanamide | HCID 2107517 | 24.1% |
Reaction Steps
Prepared according to the method of example 18, using 5-quinolinamine (250 mg) and cyclopentanepropanoic acid (270 mg). Purification (HPLC, Symmetry—0.1% aqueous trifluoroacetic acid/acetonitrile) followed by recrystallisation from methanol/ethyl acetate gave the title compound as a colourless solid (112 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07408065B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-a80433abb70a48ee91e47047b46d9861 |
| Source note | uspto-grants-2008_08 |