HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylcyclopropanecarboxylic acid → 1-Cyclohexylcyclopropane-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylcyclopropanecarboxylic acid | HCID 80206 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Cyclohexylcyclopropane-1-carboxylic acid | HCID 53745023 | 57.8% |
Reaction Steps
To 1-phenyl-cyclopropanecarboxylic acid (0.500 g) in acetic acid (2 mL) was added Adams catalyst (0.050 g) in ethanol (0.3 mL). The reaction was left to stir for 48 hours under 5 bar of hydrogen. The reaction was filtered, washing with ethanol (10 mL) and water (10 mL). The resulting solid was collected by filtration and subsequently washed with water (10 mL) to afford the sub-titled compound (0.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07408065B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-5f11a481afb645a6a92f3fb09c7e6df5 |
| Source note | uspto-grants-2008_08 |