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HRID2217820

反应详情

EQUATION

反应方程式

HRID 2217820 的结构方程式

REACTANTS

反应物

2
结构：Nc1c(Cl)ccc2nc(Cl)ccc12
HCID24820374

2,6-Dichloroquinolin-5-amine

C9H6Cl2N2

结构：O=C(O)C1(C2CCCCC2)CC1
HCID53745023

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Nc1c(Cl)ccc2nc(Cl)ccc12)C1(C2CCCCC2)CC1
HCID86013011

未命名化合物

收率 50.8%

PROCEDURE

实验过程

Prepared according to the method of example 1(a), using 2,6-dichloro-5-quinolinamine (prepared as described in Example 1(d)) (0.3 g) and 1-cyclohexyl cyclopropanecarboxylic acid (Example 26(a)) (0.28 g) at 100° C. for 15 hours. Purification by chromatography (SiO2, dichloromethane as eluant) afforded the sub-title compound (0.26 g).

WORKUP

后处理

  1. customPrepared
  2. customat 100° C.
  3. customfor 15 hours
  4. customPurification by chromatography (SiO2, dichloromethane as eluant)