Peracetic Acid → HCID 86013039, compound

HRID 2217854Notes

Reaction equation

HRID 2217854 reaction equation
[CH:1]1([CH2:7][NH:8][C:9]([C:11]2[C:12]3[CH:13]=[CH:14][CH:15]=[N:16][C:17]=3[CH:18]=[CH:19][C:20]=2[CH3:21])=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(OO)(=O)C.P(Cl)(Cl)([Cl:29])=O>C(O)(=O)C>[Cl:29][C:15]1[CH:14]=[CH:13][C:12]2[C:11]([C:9]([NH:8][CH2:7][CH:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)=[O:10])=[C:20]([CH3:21])[CH:19]=[CH:18][C:17]=2[N:16]=1

Participants

5

Reactant 3

HCID 6585Peracetic AcidHCID 24813Phosphorus oxychlorideHCID 11277533HCID 11277533, compound

Product 1

HCID 86013039HCID 86013039, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Prepared according to the method of example 43(a), using N-(cyclohexylmethyl)-6-methyl-5-quinolinecarboxamide (Example 57) (3 g), peracetic acid (3.3 g, 45% in acetic acid), glacial acetic acid (20 mL) and subsequently phosphorous oxychloride (20 mL) to afford the sub-titled compound (1.5 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-160511155565401f97007187c4563820
Source dataset
uspto-grants-2008_08
Patent number
US07408065B2

Reaction notes

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