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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2217894Generated: November 1, 2026

Cyclohexanepropanoic acid → N-(2,6-Dichloro-5-quinolinyl)-cyclohexanepropanamide

https://huagongshe.com/reaction/2217894

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanepropanoic acidHCID 69702—
Reactant2,6-Dichloroquinolin-5-amineHCID 24820374—
ProductN-(2,6-Dichloro-5-quinolinyl)-cyclohexanepropanamideHCID 86012849—

Reaction Steps

Prepared according to the method of example 62(a), using 2,6-dichloroquinolin-5-amine (example 1(d)) (0.5 g) and cyclohexanepropionic acid (1.2 mL). The resulting precipitate was filtered and washed with acetone. The precipitate was further washed with water and then ether to give the sub-title compound as a solid (0.248 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07408065B2
Source datasetuspto-grants-2008_08
ORD IDord-a3b9ff56b53c43c195568aaeca3bbc90
Source noteuspto-grants-2008_08