4-Methoxybenzyl alcohol → HCID 10195772, compound

HRID 2217988Notes

Reaction equation

HRID 2217988 reaction equation
[Cl:1][C:2]1[S:6][C:5]([S:7]([NH:10][C:11]2[C:16](Br)=[N:15][C:14]([Br:18])=[CH:13][N:12]=2)(=[O:9])=[O:8])=[CH:4][CH:3]=1.[CH3:19][O:20][C:21]1[CH:28]=[CH:27][C:24]([CH2:25][OH:26])=[CH:23][CH:22]=1>>[Br:18][C:14]1[N:15]=[C:16]([O:26][CH2:25][C:24]2[CH:27]=[CH:28][C:21]([O:20][CH3:19])=[CH:22][CH:23]=2)[C:11]([NH:10][S:7]([C:5]2[S:6][C:2]([Cl:1])=[CH:3][CH:4]=2)(=[O:9])=[O:8])=[N:12][CH:13]=1

Participants

3

Reactant 2

HCID 77384-Methoxybenzyl alcoholHCID 10288068HCID 10288068, compound

Product 1

HCID 10195772HCID 10195772, compoundYield 90.1%

Procedure

Prepared by the method of Example 20b using 5-chloro-N-(3,5-dibromo-2-pyrazinyl)-2-thiophenesulphonamide (Example 8) (0.32 g) and 4-methoxybenzylalcohol (0.1 g) to give the product (0.32 g).

Workup

  1. customPrepared by the method of Example 20b

Sources & evidence

ORD record
ord-eb9924cebf294a3bb083bd39fa85cc67
Source dataset
uspto-grants-2008_08
Patent number
US07410972B2

Reaction notes

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