Phenylboronic Acid → HCID 11210622, compound

HRID 2218013Notes

Reaction equation

HRID 2218013 reaction equation
Cl[C:2]1[C:3]2[CH:14]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:12]=[CH:11][C:4]=2[N:5]([CH3:10])[C:6](=[O:9])[CH2:7][N:8]=1.C1(B(O)O)C=CC=CC=1.[Cl:30][C:31]1[CH:32]=[C:33](B(O)O)[CH:34]=[CH:35][CH:36]=1>>[Cl:30][C:31]1[CH:36]=[C:35]([C:2]2[C:3]3[CH:14]=[C:13]([C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=4)[CH:12]=[CH:11][C:4]=3[N:5]([CH3:10])[C:6](=[O:9])[CH2:7][N:8]=2)[CH:34]=[CH:33][CH:32]=1

Participants

4

Reactant 3

HCID 66827Phenylboronic AcidHCID 2734323(3-Chlorophenyl)boronic acidHCID 69289305HCID 69289305, compound

Product 1

HCID 11210622HCID 11210622, compoundYield 37%

Procedure

Prepared from 5-chloro-1-methyl-7-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one using the same method described for Example 9 and instead of using benzene boronic acid, we used 3-chlorophenyl boronic acid. The title compound was obtained as a pale yellow solid, (yield=37%).

Sources & evidence

ORD record
ord-0168a8e921584b0493c7205bc4aa7efd
Source dataset
uspto-grants-2008_08
Patent number
US07410963B2

Reaction notes

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