2-Methoxyphenylboronic acid → HCID 11348835, compound

HRID 2218019Notes

Reaction equation

HRID 2218019 reaction equation
Cl[C:2]1[C:3]2[CH:14]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:12]=[CH:11][C:4]=2[N:5]([CH3:10])[C:6](=[O:9])[CH2:7][N:8]=1.C(C1C=C(B(O)O)C=CC=1)=O.[CH3:32][O:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=1B(O)O>>[CH3:32][O:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=1[C:2]1[C:3]2[CH:14]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:12]=[CH:11][C:4]=2[N:5]([CH3:10])[C:6](=[O:9])[CH2:7][N:8]=1

Participants

4

Reactant 3

HCID 27339582-Methoxyphenylboronic acidHCID 27343563-Formylphenylboronic acidHCID 69289305HCID 69289305, compound

Product 1

HCID 11348835HCID 11348835, compoundYield 58%

Procedure

Prepared from 5-chloro-1-methyl-7-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one using the same method described for Example 9 and instead of using 3-formylbenzene boronic acid, we used 2-methoxyphenyl boronic acid. The title compound (87 mg) was obtained as a beige solid, (yield=58%).

Sources & evidence

ORD record
ord-f35c067d1df945f980cfab5193d0a5f6
Source dataset
uspto-grants-2008_08
Patent number
US07410963B2

Reaction notes

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