HCID 69300355, compound → HCID 69300320, compound

HRID 2218126Notes

Reaction equation

HRID 2218126 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([NH:16][C:17]([NH:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[CH3:26])=[O:18])[CH:5]=[CH:6][C:7]=1[C:8]1[C:9]([O:14]C)=[N:10][CH:11]=[CH:12][CH:13]=1>Cl>[F:1][C:2]1[CH:3]=[C:4]([NH:16][C:17]([NH:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[CH3:26])=[O:18])[CH:5]=[CH:6][C:7]=1[C:8]1[C:9](=[O:14])[NH:10][CH:11]=[CH:12][CH:13]=1

Participants

3

Reactant 1

HCID 69300355HCID 69300355, compound

Product 1

HCID 69300320HCID 69300320, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

1-[3-Fluoro-4-(2-methoxypyridin-3-yl)phenyl]-3-o-tolylurea (P12) (0.150 g, 0.43 mmol) in ethanolic hydrochloric acid (10 mL) was stirred at reflux for 8 hours. The reaction mixture was then allowed to cool, and concentrated to afford the title compound as a solid.

Workup

  1. temperatureat reflux for 8 hours
  2. temperatureto cool
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-f289649022844e9ab1f132d813821106
Source dataset
uspto-grants-2008_08
Patent number
US07410984B2

Reaction notes

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