Hydrochloric Acid → HCID 10051520, compound

Participants

Reaction Steps

Potassium trimethylsilanolate (0.035 g, 0.25 mmol) was added to a solution of [methyl-(4-{2-oxo-3-[4-(3-o-tolyl-ureido)phenyl]-2H-pyridin-1-ylmethyl}phenyl)amino]acetic acid ethyl ester (0.90 g, 0.17 mmol) in tetrahydrofuran (5 mL) and the mixture stirred at room temperature for 2 hours. A solution of hydrochloric acid in diethyl ether (1 M, 1 mL) was added and solvent evaporated. The residue was triturated with diethyl ether, filtered and dried to give the title compound as a solid.

Provenance & Evidence