HuagongsheHuagongshe Chemistry Print Report · For research reference only
Urea → 3-(4-{2-Oxo-3-[4-(3-o-tolyl-ureido)phenyl]piperidin-1-yl}phenyl)propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | 3-{4-[3-(4-Nitrophenyl)-2-oxo-2H-pyridin-1-yl]phenyl}propionic acid ethyl ester | HCID 69300334 | — |
| Product | 3-(4-{2-Oxo-3-[4-(3-o-tolyl-ureido)phenyl]piperidin-1-yl}phenyl)propionic acid | HCID 10479888 | — |
Reaction Steps
The title compound was prepared from 3-{4-[3-(4-nitrophenyl)-2-oxo-2H-pyridin-1-yl]phenyl}propionic acid ethyl ester which is prepared as described in Preparation 24 with subsequent hydrogenation, urea formation, and hydrolysis steps analogous to the procedures of Preparation 23, Preparation 9 and Example 1 respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07410984B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-b81abd9acd0a40c2970d469425798c38 |
| Source note | uspto-grants-2008_08 |