Glyoxylic Acid → HCID 10775091, compound

HRID 221822Notes

Reaction equation

HRID 221822 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10](=O)[CH3:11])=[CH:5][CH:4]=1.[C:13]([OH:17])(=O)[CH:14]=O.O.[NH2:19][NH2:20]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:10]([CH3:11])=[N:20][NH:19][C:13](=[O:17])[CH:14]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 760Glyoxylic AcidHCID 24654Hydrazine hydrate (1:1)HCID 312311-(p-Methoxyphenyl)-2-propanone

Product 1

HCID 10775091HCID 10775091, compound

Procedure

5-(4-methoxyphenyl)-6-methyl-2H-pyridazin-3-one was prepared from 1-(4-methoxy-phenyl)propan-2-one and glyoxalic acid and hydrazine hydrate using the procedure described in Example 86 Step 1; Mp 255-256° C.; MS m/z 203 (M+H).

Sources & evidence

ORD record
ord-cfcf6f37a61c4cf390a42a965cff0354
Source dataset
uspto-grants-2012_06
Patent number
US08207168B2

Reaction notes

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