Piperidine → 6-Bromo-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-3H-imidazo[4,5-b]pyridine

HRID 2218365Notes

Reaction equation

HRID 2218365 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[N:10]=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][CH2:20]Cl)=[CH:13][CH:12]=3)[NH:8][C:5]2=[N:6][CH:7]=1.[NH:22]1[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[Br:1][C:2]1[CH:3]=[C:4]2[N:10]=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][CH2:20][N:22]4[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]4)=[CH:13][CH:12]=3)[NH:8][C:5]2=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 178478466HCID 178478466, compound

Product 1

HCID 1784194416-Bromo-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-3H-imidazo[4,5-b]pyridine

Procedure

The title compound was prepared from 6-bromo-2-[4-(3-chloropropoxy)phenyl]-3H-imidazo[4,5-b]pyridine and piperidine using the method described in Example 46.

Sources & evidence

ORD record
ord-eabd96b64eb743239d3ae0b3d28c911b
Source dataset
uspto-grants-2008_08
Patent number
US07410966B2

Reaction notes

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