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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2218373Generated: November 1, 2026

4-Hydroxypyrrolidine → 1-{3-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)phenoxy]-2-hydroxypropyl}pyrrolidin-3-ol

https://huagongshe.com/reaction/2218373

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxypyrrolidineHCID 98210—
ReactantHCID 178419439HCID 178419439—
Product1-{3-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)phenoxy]-2-hydroxypropyl}pyrrolidin-3-olHCID 178516510—

Reaction Steps

The title compound was prepared from 6-bromo-2-[4-(oxiran-2-ylmethoxy)phenyl]-3H-imidazo[4,5-b]pyridine and pyrrolidin-3-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07410966B2
Source datasetuspto-grants-2008_08
ORD IDord-5fd30363887b4c3f8cf70f52a99f56cf
Source noteuspto-grants-2008_08