HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1-methanesulfonylpyrrolidine → 6-Chloro-N-[1-(methylsulfonyl)-3-pyrrolidinyl]-2-{4-[2-(4-morpholinyl)ethoxy]phenyl}-1H-imidazo[4,5-b]pyridin-7-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1-methanesulfonylpyrrolidine | HCID 53393253 | — |
| Reactant | HCID 178478272 | HCID 178478272 | — |
| Product | 6-Chloro-N-[1-(methylsulfonyl)-3-pyrrolidinyl]-2-{4-[2-(4-morpholinyl)ethoxy]phenyl}-1H-imidazo[4,5-b]pyridin-7-amine | HCID 11756454 | 19% |
Reaction Steps
By a procedure similar to that of Example 207 but using 6,7-dichloro-2-[4-(2-morpholin-4-ylethoxy)phenyl]-3H-imidazo[4,5-b]pyridine (Example 206) and 1-(methylsulfonyl)pyrrolidin-3-amine, the title compound was obtained in 19% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07410966B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-6f76048c0d7e40f5aaa0314bf3ab65af |
| Source note | uspto-grants-2008_08 |