HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl (1R,2S)-2-aminocyclohexane-1-carboxylate hydrochloride → ethyl(1r,2s)-2-aminocyclohexanecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl (1R,2S)-2-aminocyclohexane-1-carboxylate hydrochloride | HCID 2724641 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | ethyl(1r,2s)-2-aminocyclohexanecarboxylate | HCID 818060 | 92.2% |
Reaction Steps
Ethyl-cis-2-amino-1-cyclohexanecarboxylate hydrochloride (750 mg) was suspended in 1 N NaOH (pH =12). The aqueous layer was extracted with CH2Cl2, washed with brine, dried over Na2SO4 and evaporated to give the crude ethyl-cis-2-amino- 1-cyclohexanecarboxylate (570 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07411093B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-0a8bcbe64fde474dac87d58794b79a2c |
| Source note | uspto-grants-2008_08 |