HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68973979, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59718674 | HCID 59718674 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68973979 | HCID 68973979 | — |
Reaction Steps
In an analogous manner to that described in Example 1d), the treatment of the (S)-3-tert-butoxycarbonylamino-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carboxylic acid 2,2,2-trifluoro-ethyl ester with hydrochlorid acid (37%) in dioxane yielded (98% of theory) the title compound as an off-white solid; MS (m/e): 304 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414049B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-b89b5ef1211048c982b5e93b3fdd6366 |
| Source note | uspto-grants-2008_08 |