Hydrochloric Acid → HCID 87692339, compound

Participants

Reaction Steps

In an analogous manner to that described in Example 1d), the treatment of the (S)-3-tert-butoxycarbonylamino-4-oxo-5-(2,2,2-trifluoro-ethyl)-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carboxylic acid 2,2,2-trifluoro-ethyl ester [Example 10a)] with hydrochlorid acid (37%) in dioxane yielded (93% of theory) the title compound as a light yellow solid; MS (m/e): 386 (M+H)+.

Provenance & Evidence