HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68975256, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59718702 | HCID 59718702 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68975256 | HCID 68975256 | — |
Reaction Steps
In an analogous manner to that described in Example 1d), the treatment of the (S)-5-(2-benzyloxy-ethyl)-3-tert-butoxycarbonylamino-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carboxylic acid 2-benzyloxy-ethyl ester with hydrochlorid acid (37%) in dioxane yielded quantitatively the title compound as a viscous light yellow oil; MS (m/e): 490 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414049B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-744c2b9dcd824973b9e918987605a76f |
| Source note | uspto-grants-2008_08 |