HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-(Pyrrolidin-1-yl)ethoxy)aniline → HCID 178419007, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-(Pyrrolidin-1-yl)ethoxy)aniline | HCID 6493749 | — |
| Reactant | 5-chloro-3-(hydroxymethylidene)-1H-indol-2-one | HCID 178419036 | — |
| Product | HCID 178419007 | HCID 178419007 | 79% |
Reaction Steps
In a manner similar to that described in Example 231, 4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine (632 mg, 1.2 equiv.) and 5-chloro-3-hydroxymethylene-1,3-dihydro-indol-2-one (500 mg, 2.56 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (775 mg, 79%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414054B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-6d1434cc3da244afbf8c4a78657fcc4e |
| Source note | uspto-grants-2008_08 |