Sodium Hydroxide → HCID 178511378, compound

Participants

Reaction Steps

A 1N NaOH solution (5.96 mL) is added slowly to a stirred suspension of 1-hydroxy-isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide hydrochloride (1.81 g, 5.96 mmol) in CH3OH (10 mL) at ambient temperature under nitrogen. The resultant mixture is allowed to stir for 30 minutes. The mixture is then concentrated at 50° C. under vacuum to give a 1.87 g of the title compound (96% yield) as a white powder.

Provenance & Evidence