HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyrimidine → HCID 23726019, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | HCID 178434973 | HCID 178434973 | — |
| Product | HCID 23726019 | HCID 23726019 | 73% |
Reaction Steps
As described for Example 49, 3-(4-bromo-phenyl)-4-(1H-imidazol-4-yl)-5-methyl-isoxazole (61 mg, 0.2 mmol) using 2-chloropyrimidine instead of 4-fluoroacetophenone was converted to the title compound (56 mg, 73%) which was obtained as a light yellow solid. MS: m/e=382.0/384.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-baadb35e64fb4768ae2fcd8e3969a70e |
| Source note | uspto-grants-2008_08 |