HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Chloromethyl)-5-methyl-1,2-oxazole → HCID 23725695, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Chloromethyl)-5-methyl-1,2-oxazole | HCID 2735763 | — |
| Reactant | HCID 178434979 | HCID 178434979 | — |
| Product | HCID 23725695 | HCID 23725695 | 63% |
Reaction Steps
As described for Example 67, 4-(2-benzyloxymethyl-1H-imidazol-4-yl)-5-methyl-3-phenyl-isoxazole (100 mg, 0.29 mmol) using 3-(chloromethyl)-5-methylisoxazole instead of benzyl bromide was converted to the title compound (80 mg, 63%) which was obtained as a light yellow gum. MS: m/e=441.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-f35c47b05f304ac1b38539c20d76e167 |
| Source note | uspto-grants-2008_08 |