HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 67421314, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | (3-Ethoxycarbonylphenyl)boronic acid | HCID 3249312 | — |
| Reactant | HCID 178434992 | HCID 178434992 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 67421314 | HCID 67421314 | 32% |
Reaction Steps
As described for Example 3, 3-(3-fluoro-phenyl)-4-(1H-imidazol-4-yl)-5-methyl-isoxazole (2.43 g, 10 mmol) was converted, using of 3-ethoxycarbonylphenylboronic acid instead of 4-fluorophenylboronic acid, through chromatography (SiO2, ethyl acetate: hexane=20:10) to the title compound (1.26 mg, 32%) which was obtained as a light yellow solid. MS: m/e=392.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414061B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-3e2da6132aba4b05a019aa8ed957e45b |
| Source note | uspto-grants-2008_08 |