Thionyl Chloride → HCID 87392931, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 5-methoxymethyl-3-phenyl-isoxazole-4-carboxylic acid (10.0 g, 43.0 mmol) in thionyl chloride (20 mL) was heated at 60° C. for 3 h. The resulting mixture was concentrated under reduced pressure to afford the crude title compound (11.16 g, 100%) which was obtained as a light yellow liquid. The crude product was directly used in the next step without further purification.

Provenance & Evidence