5-Bromopyrimidine → HCID 11544349, compound

HRID 2219477Notes

Reaction equation

HRID 2219477 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[C:16]([NH2:17])=[CH:15][CH:14]=[C:13]([CH3:18])[N:12]=2)=[O:10])=[N:6][CH:7]=1.Br[C:20]1[CH:21]=[N:22][CH:23]=[N:24][CH:25]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:20]3[CH:21]=[N:22][CH:23]=[N:24][CH:25]=3)=[CH:15][CH:14]=[C:13]([CH3:18])[N:12]=2)=[O:10])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 783445-BromopyrimidineHCID 86607569HCID 86607569, compound

Product 1

HCID 11544349HCID 11544349, compound

Procedure

The title compound, MS (ISP): m/e=325.0 (M+H+), was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (5-fluoro-pyridin-2-yl)-amide in accordance with the general method of example 20 using 5-bromopyrimidine instead of 3-Bromopyridine.

Sources & evidence

ORD record
ord-bcdfb60294a6416daf9c47719831fab9
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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