HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromopyrimidine → 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid (4-trifluoromethyl-thiazol-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromopyrimidine | HCID 78344 | — |
| Reactant | HCID 86607572 | HCID 86607572 | — |
| Product | 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid (4-trifluoromethyl-thiazol-2-yl)-amide | HCID 11717841 | — |
Reaction Steps
The title compound, light yellow solid, MS (ISP): m/e=381.0 (M+H+), was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (4-trifluoromethyl-thiazol-2-yl)-amide in accordance with the general method of example 20 using 5-bromopyrimidine instead of 3-bromo-pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-bb400c23bb5b4fe8938783940ff6532c |
| Source note | uspto-grants-2008_08 |