5-Bromopyrimidine → HCID 11573922, compound

HRID 2219535Notes

Reaction equation

HRID 2219535 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([C:13]2[C:18]([NH2:19])=[CH:17][CH:16]=[C:15]([CH3:20])[N:14]=2)=[O:12])=[N:6]1.Br[C:22]1[CH:23]=[N:24][CH:25]=[N:26][CH:27]=1>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([C:13]2[C:18]([NH:19][C:22]3[CH:23]=[N:24][CH:25]=[N:26][CH:27]=3)=[CH:17][CH:16]=[C:15]([CH3:20])[N:14]=2)=[O:12])=[N:6]1

Participants

3

Reactant 2

HCID 783445-BromopyrimidineHCID 86607587HCID 86607587, compound

Product 1

HCID 11573922HCID 11573922, compound

Procedure

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid [1-(2-methoxy-ethyl)-1H-pyrazol-3-yl]-amide in accordance with the general method of example, step using 5-Bromopyrimidine instead of 3-bromopyridineto yield the final compound as a off-white solid, MS (ISP): m/e=354.1 (M+H+).

Sources & evidence

ORD record
ord-2a5cf8adf3764ef7bf39905faebf0bc5
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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