HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylthiazole → 6-Methyl-3-(4-methyl-thiazol-2-ylamino)-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylthiazole | HCID 74143 | — |
| Reactant | 3-Bromo-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide | HCID 86607590 | — |
| Product | 6-Methyl-3-(4-methyl-thiazol-2-ylamino)-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide | HCID 11631275 | — |
Reaction Steps
The title compound, was prepared from 3-Bromo-6-methyl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide in accordance with the general method of Example 78, step 3 using 2-Amino-4-methylthiazole instead of 3-Amino-1-methyl-pyrazole to yield the final compound as a yellow solid, MS (ISP): m/e=329.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-128604df8d6f413497e2cdd3d87560ae |
| Source note | uspto-grants-2008_08 |